Name: FOX-04 Dri (5mg) - Peptide Sphere
SKU: FOX04DRI-5MG-1624
Price: 138.75 USD
Availability: OutOfStock

Description

FOXO4-DRI (Senolytic Peptide)

FOXO4-DRI is a synthetic D-retro-inverso peptide designed to selectively disrupt the interaction between the FOXO4 protein and p53 in senescent cells. By interfering with this pathway, FOXO4-DRI is researched for its potential as a senolytic agent — capable of inducing apoptosis (programmed cell death) in senescent cells while sparing healthy ones.

Research Properties:

Senolytic Activity: Studied for its ability to selectively clear senescent (zombie) cells that accumulate with age and contribute to chronic inflammation and tissue dysfunction.
Anti-Aging & Tissue Regeneration: Investigated for potential to reduce age-related tissue damage and promote healthier tissue function.
Longevity Research: Explored in models for its possible role in extending healthspan and lifespan by targeting one of the hallmarks of aging (cellular senescence).

Administration in Research:

Subcutaneous injection

Important Research Notes:

FOXO4-DRI is considered a potent senolytic and is still highly experimental.
Researchers should be aware of potential interactions with compounds such as Rapamycin, Quercetin, and corticosteroids. A washout period is commonly observed in research protocols.
Healthy cells in organs with limited regenerative capacity (including reproductive organs) may also be affected in some models.

For Research Use Only. Not for human consumption. FOXO4-DRI is intended strictly for laboratory research and in-vitro experimentation.

CORE FEATURES

FOXO4-DRI: A Research Peptide Overview

FOXO4-DRI, a synthetic peptide based on the Forkhead box O4 (FOXO4) transcription factor, has gained attention in research for its role in targeting cellular senescence. This peptide is specifically designed to disrupt interactions between FOXO4 and p53, promoting the clearance of senescent cells and enhancing tissue regeneration. Its unique mechanism has positioned FOXO4-DRI as a promising candidate for studying aging and related conditions.

Key Research Areas:

Senescence Clearance: FOXO4-DRI is widely studied for its ability to selectively target and eliminate senescent cells, which accumulate with age and contribute to tissue dysfunction.
Anti-Aging Research: Researchers are investigating how FOXO4-DRI may influence aging processes by improving cellular health and enhancing tissue repair.
Degenerative Diseases: Preliminary studies have explored its potential applications in conditions linked to senescence, such as osteoarthritis and other age-related disorders.

Why Choose FOXO4-DRI for Research?

FOXO4-DRI is highly specific in its action, making it a valuable tool for studying the mechanisms of cellular senescence and its impact on aging and disease. Its stability and targeted design enable researchers to explore therapeutic pathways in aging and regenerative medicine.

Important Note:

FOXO4-DRI is offered exclusively for laboratory research purposes. It is not approved for human or animal use, nor is it intended to diagnose, treat, cure, or prevent any disease or condition.